p450 - publications

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1. Ther Drug Monit. 2012 Apr;34(2):121-3.

Suspected Opioid Overdose Case Resolved by CYP2D6 Genotyping.

Shaw KD, Amstutz U, Jimenez-Mendez R, Ross CJ, Carleton BC.

*Division of Translational Therapeutics, Department of Paediatrics, Faculty of
Medicine, University of British Columbia †Pharmaceutical Outcomes Programme, BC
Children's Hospital ‡Canadian Pharmacogenomics Network for Drug Safety §Child and
Family Research Institute ¶Centre for Molecular Medicine and Therapeutics,
University of British Columbia, Vancouver, British Columbia, Canada.

ABSTRACT: A 14-year-old female with suspected narcotic overdose had CYP2D6
genotyping performed to verify opiate intoxication. The role of pharmacogenetics
in pain management and individualization of opiate pharmacotherapy is discussed.

PMID: 22406651 [PubMed - in process]